OB/Gyn | MedPage Today - Lasofoxifene vaginal atrophy lead investigators
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However HRT, especially if administered long-term, may lead to an increased .. A pharmacodynamic investigation was performed in a randomized, placebo . Efficacy of lasofoxifene treatment on vulvar and vaginal atrophy. Lasofoxifene is a selective estrogen receptor modulator (estrogen . A day, randomized, placebo-controlled, investigator blind, multiple dose study . Changes in signs and self-assessed symptoms of vaginal atrophy, cognitive .. Developing a SERM: stringent preclinical selection criteria leading to an.